THC effective in Tourette syndrome in a 6-week trial (International Association for Cannabis as Medicine)
Question:
<gnlw…@comcast.net> wrote in message
news:aRadnX10KsIA1kujXTWcrg@comcast.com… > Dumb question. What is THC?
Tetrahydracannabinol (or something like that!) Pot, weed, cannibus Jo – Hide quoted text — Show quoted text -> Lisa > "Randall Bart" <Barti…@att.spam.net> wrote in message > news:qhk0dvobl8mqlqadaf51m1n866ud8l5b18@4ax.com… > > From: Richard Lake <rl…@mapinc.org> > > Date: Sun, 11 May 2003 18:48:23 -0400 > > Subject: [medicalmarijuanafreedom] IACM-Bulletin of 11 May 2003 > > * Science: THC effective in Tourette syndrome in a 6-week trial > > Science: THC effective in Tourette syndrome in a 6-week trial > > A double-blind placebo-controlled study with 24 patients suffering > > from Tourette syndrome was conducted at the Medical School of > > Hannover, Germany. The 6-week trial confirmed results of two > > earlier short-term studies by Dr. Kirsten Mueller-Vahl and > > colleagues that THC is effective in the reduction of tics. > > The Tourette syndrome is a complex neurological-psychiatric > > disorder characterized by motor tics (sudden spasms especially in > > the face, the neck and the shoulders) and one or more vocal tics. > > In many cases, it is associated with behavioural problems or > > psychopathologies (autoaggression, disturbed attention, etc.). > > Presently, neuroleptics are the most effective drugs. However, > > neuroleptics are not effective in all patients and in many cases, > > are not well tolerated. > > Patients were treated over a period of 6 weeks. The dosage was > > titrated to the target dosage of 10 mg THC. Starting at 2.5 > > mg/day, the dose was increased by increments of 2.5 mg/day > > every 4 days. Tic severity was rated using several established > > scales. > > Seven patients dropped out of the study or had to be excluded, but > > only one due to side effects. Application of THC resulted in a > > significant improvement of tic severity. No serious adverse > > effects occurred. Authors concluded that the results provide > > more evidence that THC is effective and safe in the treatment of > > tics. > > (Source: Mueller-Vahl KR, Schneider U, Prevedel H, Theloe K, > > Kolbe H, Daldrup T, Emrich > > HM. Delta-9-tetrahydrocannabinol (THC) is effective in the > > treatment of tics in Tourette syndrome: a 6-week randomized trial. > > J Clin Psychiatry 2003;64(4):459-465) > > (More at the IACM-Bulletin archives: http://www.cannabis-med.org/) > > International Association for Cannabis as Medicine (IACM) > > Arnimstrasse 1A > > D-50825 Cologne > > Germany > > Phone: 221-9543 9229 > > Fax: 221-130 05 91 > > Email: i…@cannabis-med.org > > http://www.cannabis-med.org > > If you want to be deleted from or added to the IACM-Bulletin > > mailing list or if you want to change your e-mail address please > > visit > > www.cannabis-med.org/english/subscribe.htm. You may choose > > between different languages (English, German, French, Dutch, > > Italian, Spanish and Swedish). > > — > > RB |
